![]() Ginger ( Zingiber officinale) is a spice with a long history of use as traditional remedy for nausea and vomiting. The antiemetic drugs most frequently prescribed in Europe and Italy are domperidone, a dopamine receptor antagonist, and ondansetron, a 5‐HT 3 antagonist.Ĭurrent evidence shows that ondansetron but not domperidone is effective for the treatment of AGE‐associated vomiting in the emergency setting. Nearly 80% of Italian pediatricians prescribe antiemetic drugs to children with AGE, mostly off‐label. Vomiting is the presenting symptom in up to 75% of children with acute gastroenteritis (AGE), where it contributes to fluid loss, failure of oral rehydration therapy, and emergency admission to the hospital. Vomiting is a common symptom in childhood and has many causes, ranging from self‐limited to life‐threatening conditions. ![]()
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